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NEW YORK -- Defending champion Andy Murray could face top-seeded Novak Djokovic only in the semifinals at the U.S. Open, while Rafael Nadal and Roger Federer -- who have never played each other at Flushing Meadows -- might meet in the quarter-finals. Murray earned his first Grand Slam championship by beating Djokovic in the 2012 U.S. Open final, then added a second by beating the No. 1-ranked Serb in the Wimbledon title match last month. But there cant be a rematch in New York in the final, thanks to Thursdays draw. "Coming to the U.S. Open last year, Id never won a Grand Slam. I didnt know if I was ever going to win one," Murray said at the draw ceremony. "A lot of people would say ... like, Hes good enough to win a Grand Slam. Hes going to win one. But the more finals you lose in, the more you start to doubt yourself and think, Is it ever going to happen? Getting that weight off my shoulders last year was huge." Play at the years last Grand Slam tournament begins Monday. In addition to No. 2 Nadal against No. 7 Federer, a 17-time major champion who has his lowest seeding at the U.S. Open since he was 13th in 2002, the other possible mens quarter-finals are 2011 champion Djokovic versus 2009 champion Juan Martin del Potro, No. 3 Murray versus No. 5 Tomas Berdych, and No. 4 David Ferrer versus No. 8 Richard Gasquet or 10th-ranked Canadian Milos Raonic. Federer, who owns five U.S. Open titles, and Nadal also were set up for a possible quarter-final at Wimbledon this year, but that never materialized: Nadal lost in the first round, and Federer in the second. The potential womens quarter-finals at the U.S. Open are No. 1 Serena Williams against No. 8 Angelique Kerber, No. 2 Victoria Azarenka against No. 7 Petra Kvitova, No. 3 Agnieszka Radwanska against No. 5 Li Na, and No. 4 Sara Errani against No. 6 Caroline Wozniacki. The woman who originally was seeded third in the tournament, 2006 champion Maria Sharapova, withdrew Wednesday because of a right shoulder injury. Raonic, from Thornhill, Ont., joins Vasek Pospisil of Vernon, B.C., in the mens main draw. Montreals Eugenie Bouchard and Aleksandra Wozniak of Blainville, Que., are in the main womens draw. More Canadians could advance to the main draw. Torontos Sharon Fichman, Stephanie Dubois of Laval, Que., and Frank Dancevic of Niagara Falls, Ont., all won their opening qualifying matches Thursday. Torontos Steven Diez and Ottawas Jesse Levine lost the opening round of qualifying. Williams 16 Grand Slam titles include four at the U.S. Open, including last year. Her first-round opponent will be 2010 French Open champion Francesca Schiavone. Williams could play 15th-seeded Sloane Stephens of the United States in the fourth round; Stephens won their Australian Open quarter-final in January. "I take every match really seriously. I dont look too far in the draw. I just look at the first one," Williams said. "For me, my competition comes with each match. Every match is going to be a very, very tough competition for me, and I just stay focused on one at a time." Williams has won 77 of her past 81 matches, and was asked Thursday whether she is playing better than she ever has. "I hope not," Williams answered. "I always like to hope I can do better, so well see." Her older sister, 2000-01 U.S. Open champion Venus, is unseeded and was drawn to play No. 12 Kirsten Flipkens, a Wimbledon semifinalist last month, in the first round next week. Djokovic and 2010 U.S. Open champion Nadal, who recently overtook Murray at No. 2 in the rankings, could meet only in the final. Theyve already met in five Grand Slam championship matches, including in New York in 2010 and 2011. One intriguing earlier matchup for 12-time major title winner Nadal could come in the fourth round, when he might have to play six-foot-10 John Isner, a big-serving American who is seeded 13th and pushed the Spaniard to five sets at the French Open two years ago. Nadal was drawn to play another American, 21-year-old Ryan Harrison, in the first round. Djokovic, who has reached at least the semifinals at the U.S. Open each of the past six years, could face 25th-seeded Grigor Dimitrov in the third round. Dimitrov surprisingly beat Djokovic on clay at the Madrid Masters in May, although Djokovic won their matchup less than a month later at the French Open. In the second round, Djokovic might play Lukas Rosol, the man who upset Nadal at Wimbledon while ranked 100th in 2012, or Benjamin Becker, who defeated Andre Agassi at the 2006 U.S. Open in the Americans last professional match. 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CLEVELAND -- Jake Arietta made a brief run at a no-hitter and ended another 71-year pause between celebrations for the Chicago Cubs and their faithful fans.Not only are they back in the World Series, theyve won there again.One more drought quenched, one more to go.Arrieta carried a no-hit bid into the sixth inning, Kyle Schwarber drove in two runs and the Cubs brushed off a shutout to even the Series with their first Fall Classic win in more than seven decades, 5-1 over the Cleveland Indians in Game 2 on Wednesday night.Arrieta, who pitched a no-hitter earlier this season, briefly invoked Don Larsens name by flirting with one deep in October before the Indians touched him for two hits and a run. However, the right-hander helped give Chicago just what it needed -- a split at Progressive Field -- before the Cubbies return to their Wrigley Field den for the next three games starting Friday night.Its always crazy good, Cubs manager Joe Maddon said when asked how he expected things to be on the corner of Clark and Addison for Game 3. But Id have to imagine a little bit more than that, especially coming back at 1-1. I think the folks will be jacked up about the win tonight.Its the finest venue there is in professional sports and maybe in all of sports.The Cubs hadnt won in the Series since beating Detroit 8-7 in 1945 to force a decisive Game 7, and after their latest win, hundreds of Chicago fans gathered in the pouring rain in the rows behind their first-base dugout, where they danced and sang. A few waved the familiar white and blue W flags.They hope to do it three more times.The big-swinging Schwarber, who made it back for Chicagos long-awaited Series return after missing six months with an injured left knee, hit an RBI single in the third off Clevelands Trevor Bauer and had another in the Cubs three-run fifth -- highlighted by Ben Zobrists run-scoring triple.In Game 1, Schwarber doubled and walked.No, its not that easy, first off. Baseballs a crazy game, he said.Even the presence of star LeBron James and the NBA champion Cavaliers, sporting their new rings, couldnt stop the Indians from losing for the first time in six home games this postseason.And Cleveland manager Terry Franconas magical touch in October finally fizzled as he dropped to 9-1 in Series games.We gave up nine hits, eight walks, two errors, and we only gave up five runs, Francona said. For us to win, we generally need to play a clean game, and we didnt do that.With rain in the forecast, Major League Baseball moved the first pitch up an hour in hopes of avoiding delays or a postponement.It turned out to be a good call as the game went on without a hitch and ended after more than four hours as light rain was beginning to fall.Arrieta and the Cubs provided the only storm.The bearded 30-year-old coasted through five innings without allowing a hit, and his no-hit bid was the longest in a Series game since Jerry Koosman of the New York Mets tossed six no-hit innings in 1969.For a brief period, Arrieta looked as if he might challenge Larsens gem -- a perfect game -- in 1956 before Indians second baseman Jason Kipnis, a die-hard Cubs fan as a kid, doubled with one out in the sixth .Arrieta has two career no-hitters, iin fact, including the only one in the majors this year.ddddddddddddI knew I hadnt given up a hit all the way to the sixth, Arietta said. Thats really not the focus in a game like this. Whether they get a hit or not really doesnt affect the way you continue to approach that lineup, especially with a five-run lead.Kipnis was impressed.We didnt get much going, he said. You have to tip your hat to Arietta. He was awesome.Cubs lefty Mike Montgomery replaced Arrieta and worked two scoreless innings before Aroldis Chapman came in and unleashed his 103 mph heat while getting the last four outs in his Series debut.The teams will have an off day before the series resumes with Game 3 at Wrigley, which will host its first Series game since 1945, when tavern owner Billy Sianis was asked to leave with his pet goat, Murphy, and a curse was born.Josh Tomlin will start for the Indians, who will lose the designated hitter in the NL ballpark, against Kyle Hendricks.Schwarber might also wind up on the bench after two days as the DH. Maddon loves the way hes swinging but isnt sure hes ready to play in the outfield.Thats something Im waiting to hear from our guys, from our medical side, because obviously he looks good, he said. He looks good at the plate. Running the bases he looks pretty good so far.And the Cubs finally do, too, as they head home.Unlike his start in Toronto on Oct. 17, when his stitched cut opened up and Bauer was forced to make a bloody departure in the first inning, his finger held up fine.The Cubs, though, put a few nicks in him in 3 2/3 innings.I just wasnt sharp for whatever reason, Bauer said.The drone accident has brought attention to the quirky Bauer, and one Chicago fan tried to rattle the right-hander by sending a smaller version of the remote-controlled, flying object that cut him.Bauer posted a photo of it on Twitter, saying I see the (at)Cubs fans love me! How nice of them to send me a gift!ODDS AND ENDSFranconas nine-game winning streak was the third longest in history, trailing Joe Torre (14) and Joe McCarthy (10). . The Cubs are 7-1 this postseason when scoring first. ... The teams combined for a Series record-tying three wild pitches. ... Indians RHP Danny Salazar made his first postseason appearance since starting the 2013 AL wild-card game. ... This is the 58th time the Series has been tied 1-1. The Game 2 winner has won the title 29 times.SHORT RESTLooking ahead, Francona has already decided hell bring Kluber back on short rest for Game 4. It wasnt much of a decision, really, after the right-hander confounded the Cubs in Game 1, painting the corners for 6 1/3 innings.UP NEXTCubs: Hendricks is coming off his brilliant performance in Game 5 of the NLCS when he pitched two-hit ball for seven innings as the Cubs clinched their first pennant in 71 years. The right-hander led the majors with a 2.13 ERA.Indians: It will be an emotional night for Tomlin, who will pitch on 12 days rest with his ailing father, Jerry, in attendance. The elder Tomlin became stricken with a spinal condition in August, when Tomlin was struggling on the mound. ' ' '