Zlatan Ibrahimovic will miss his first league game of the season when Manchester United go head-to-head with Arsenal on Saturday, live on Sky Sports 1. The striker is suspended following his fifth caution of the season, which came against Swansea at the beginning of November.Boss Jose Mourinho is free to return to the dugout having served a one-game touchline ban against Swansea after admitting using abusive words towards a match official at half-time in their 0-0 league draw with Burnley in October. Meanwhile, Arsene Wenger, who is yet to record a win against a side managed by Mourinho in the Premier League, will make a late check on the fitness of Alexis Sanchez ahead of his sides trip to Old Trafford. Arsene Wenger and Jose Mourinho will come head to head when Manchester United host Arsenal Despite carrying a hamstring injury, Sanchez scored twice in Chiles 3-1 win over Uruguay in World Cup qualifying, playing 84 minutes on Tuesday.He will no be assessed by Arsenals medical team before a decision is taken on whether he is fit to play against United. Team newsManchester United are expected to field Wayne Rooney, who this week apologised to Gareth Southgate and FA technical director Dan Ashworth over images emerged of him partying into the early hours over the weekend.Rooney sat out Englands 2-2 draw with Spain on Tuesday with a minor knee injury and returned to United for treatment ahead of Saturdays match. Centre-backs Eric Bailly and Chris Smalling will miss Arsenals visit through injury whilst Luke Shaw and Antonio Valencia face races to recover from their own fitness worries. Hector Bellerin in action for Arsenal against Middlesbrough at the Emirates Stadium For the visitors Hector Bellerin (ankle) is out for a month after picking up a knock at the end of the recent draw at home to Tottenham, with the game also coming too soon for Santi Cazorla (Achilles).Lucas Perez (ankle), Per Mertesacker and Danny Welbeck (both knee) are also still missing.Opta statsManchester United have lost just one of their last Premier League meetings against Arsenal; a 3-0 defeat at the Emirates in October 2015.Mourinho is unbeaten in all 11 Premier League games he has managed against Arsene Wenger, having won five and drawn six as former Chelsea manager. Highlights - Arsenal 1-1 Tottenham This is Manchester Uniteds third worst start to a Premier League season. Should they lose on Saturday, they would sit on their joint fewest points from the opening 12 league games, level with the 04/05 season when they went on to finish third.Arsenal are the only Premier League side yet to trail away from home.Wayne Rooney is the second-top scorer in Manchester Uniteds history with 247 goals, just two behind Sir Bobby Charlton. Highlights - Swansea 1-3 Manchester United Petr Cech has kept six league clean sheets against Manchester United, which is joint top with David Seaman. The former Chelsea keeper made 196 appearances under Mourinho. Mersons predictionI think this will be a draw. Arsenal thought they could turn up in February and win, and ended up getting beaten 3-2.Wenger is moaning about Alexis Sanchez and Chile, I think hes just starting to make excuses already.Really, Arsenal should win this game on form, but with Jose Mourinhos record against Wenger, I think he has a hold over him. Im going 1-1. Arsenal manager Arsene Wenger says his relationship with Jose Mourinho will not be an important factor when they play Manchester United on Saturday I think Mourinhos record over Wenger makes a big difference. People arent really expecting United to win this, with Arsenal playing well, but Im going one each.PAUL PREDICTS: 1-1BettingManchester United are Sky Bets 6/4 favourites for the victory on Saturday, with Arsenal 9/5 while the draw is priced at 23/10. Ahead of Arsenals trip to Manchester United on Saturday, we take a look back at some of the more memorable strikes seen between the two sides over the years However, the Gunners are considerably shorter in the Premier League outright betting at 6/1 to Uniteds price of 25/1.Marcus Rashford heads a wide open first goalscorer market at 5/1, with Wayne Rooney and Olivier Giroud closely behind at 11/2 apiece.Find out what the Soccer Saturday pundits and Jamie Redknapp are backing in their Sky Bet tips here. 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