LONDON -- Garbine Muguruzas first major tournament as a reigning Grand Slam champion didnt last long.Less than a month after winning the French Open, the second-seeded Spaniard was beaten in the second round of Wimbledon on Thursday by a Slovakian qualifier ranked No. 124.In the biggest upset of the tournament so far, Jana Cepelova beat a listless Muguruza 6-3, 6-2 on Court 1 in less than an hour to reach the third round at the All England Club.Muguruza was not as sharp Thursday as she was in this tournament last year, when she lost to Serena Williams?in the final, or as she was in beating Williams in the final at Roland Garros this month for her first major championship.My energy was missing a little today, Muguruza said. From yesterday I felt a little bit tired. During the match and after the match, Im like, Tough day today, empty today.She sprayed ugly shots all over the court Thursday and finished with 22 unforced errors compared to just nine winners. Cepelova had a first-serve percentage of just more than 40 percent but still outplayed Muguruza with 14 winners and 12 errors.She played great, no fear, trying a lot of stuff that was working, Muguruza said. But my energy wasnt there. I was trying but it didnt work at all.Cepelova, Slovakias No. 5 female player, had to win three matches in qualifying to make it into the main draw. Its not the first time she has knocked off a top player. Cepelova ousted Simona Halep in the first round at Wimbledon last year, also on Court 1, and beat Williams at a tournament in Charleston in 2014.Last year I beat Halep on the same court and I had great memories, the 23-year-old Cepelova said. I am so happy.The last time a second-seeded woman lost at Wimbledon before the third round was in 2013, when?Victoria Azarenka?was beaten in the second round.Five-time Wimbledon champion Venus Williams won yet another match at the All England Club as three American women picked up victories as the tournament scrambled to get back on schedule.The eighth-seeded Williams, at 36 the oldest player seeded in the top eight at a major tournament since Martina Navratilova at Wimbledon in 1994, beat Greek qualifier Maria Sakkari 7-5, 4-6, 6-3 to reach the third round.It turned out to be an unexpectedly close, 2?-hour match between Williams, winner of seven Grand Slam titles and playing in her 19th Wimbledon, and Sakkari, making her first appearance at Wimbledon and third at a major.Williams, who had 38 winners but 31 unforced errors, won the most recent of her five Wimbledon titles in 2008. Since 2011, she has not been past the fourth round.Third-seeded Agnieszka Radwanska, the 2012 runner-up at Wimbledon, saved three match points and came back to beat 18-year-old Croatian Ana Konjuh, who accidentally stepped on a tennis ball and injured her right ankle in the next-to-last game.Radwanska pulled out the 2-6, 6-4, 9-7 victory in the second round after the 103rd-ranked Konjuh was broken while serving for the victory at 5-4 and 6-5 in the third set.Radwanska has made it to at least the semifinals at Wimbledon in three of the past four years.With play starting earlier on the outside courts after two days of bad weather, Madison Keys and Sloane Stephens?also advanced Thursday.Keys, seeded No. 9 after breaking into the top 10 for the first time this month, reached the third round with a 6-4, 4-6, 6-3 win over Kirsten Flipkens. Keys, a quarterfinalist last year, had 48 winners -- more than double the Belgian players 22.No. 18 Stephens, who reached the quarterfinals here in 2013, defeated Chinas Peng Shuai 7-6 (5), 6-2 in a first-round match that was delayed.Other womens winners included fourth-seeded Angelique Kerber advancing with a 6-1, 6-4 win over Varvara Lepchenko?and No. 5 Simona Halep, who beat Francesca Schiavone 6-1, 6-1. No. 14 Samantha Stosur was knocked out 6-4, 6-2 by 2013 runner-up Sabine Lisicki.No. 11?Timea Bacsinszky?beat Luksika Kumkhum 6-4, 6-2,?Annika Beck?ousted Britains Heather Watson 3-6, 6-0, 12-10, and Frances Kristina Mladenovic, seeded No. 31, was eliminated 6-3, 6-3 by Aliaksandra Sasnovich. Cheap New Balance Shoes UK . - The Washington Redskins have cut defensive lineman Adam Carriker and punter Sav Rocca. Cheap New Balance Shoes UK Free Shipping . -- Running backs Darren McFadden and Rashad Jennings were back at practice for the Oakland Raiders on Wednesday despite being hampered by hamstring injuries. http://www.newbalancesaleuk.com/ . First off, the fans ripped the Cubbies introduction of a fuzzy new kid-friendly mascot named "Clark". Wholesale NBA Shoes UK . The person spoke to The Associated Press on condition of anonymity because the Lions have not announced the hiring, which was first reported by ESPN. Lombardi, the grandson of former Green Bay Hall of Fame coach Vince Lombardi, has been an offensive assistant on Sean Paytons New Orleans staff since 2007. New Balance UK From China . Darren Helm scored on Detroits sixth attempt in the shootout and then Jonas Gustavsson stopped Andrew Shaws shot, lifting the Detroit Red Wings to a 5-4 win over the Chicago Blackhawks on Wednesday night. For all the hoopla surrounding Conor McGregors quest to hold two UFC championships simultaneously next month, its worth noting what Dan Henderson did nearly 10 years ago.In February 2007, Henderson won the Pride Fighting Championships 205-pound middleweight title by knocking out feared striker Wanderlei Silva. The win turned Henderson into a two-division champ, as he was already Prides welterweight champion.To this day, Henderson, 46, remains the only man to simultaneously hold two titles for a major mixed martial arts promotion. Its a feat he might have duplicated in Strikeforce had he not lost to Jake Shields in their 2010 middleweight title bout before going on to win the promotions 205-pound title the next year by stopping Rafael Cavalcante.The one title that has managed to elude Henderson during his almost 20-year career is the UFC championship. If you believe in destiny, its hard to determine whether winning a UFC title was ever in the cards for Henderson. Fate has sent mixed signals on the subject.At UFC 204?on Saturday in Manchester, England, Henderson (32-14) will get one last shot when he challenges old rival in Michael Bisping for the 185-pound title in a rematch of their 2009 bout won by Henderson.?Henderson has repeatedly stated this will mark the final fight of his storied career. He was actually ready to walk away after his last bout, an upset win over Hector Lombard in June, but agreed to a new deal with the UFC after he was offered a title shot.Im absolutely 100 percent sure this will be my last fight, Henderson said. I dont really have too many emotions about it. I dont think about it too much. Ive just been focusing on what I have to do in the fight.I think Im content with whatever happens. Obviously, the only outcome in my head is that Im going to win -- but Im ready for it to be over. Im kind of looking forward to the different chapter Im going to start after this fight.Henderson has appeared destined to win a UFC title in the past but came up empty in two prior chances.When the UFC folded the Pride roster into its ranks in 2007, Henderson received back-to-back title unification bouts at light heavyweight and middleweight. He suffered a five-round decision loss to Quinton Rampage Jackson at UFC 75 in September 2007 and was then submitted by Anderson Silva at UFC 82 in March 2008. Henderson says he has never been one to dwell on losses, but he admits those two stick out more than others.The Rampage fight was my first back from fighting in the Pride ring, Henderson said. I remembeer kind of tripping on the cage a couple times and it looking bad.dddddddddddd I thought I had done enough to win, and I remember wishing we would have fought under Pride judging [where a contest is judged as a whole] because I felt I did more damage overall in the fight.With Anderson Silva, I just had a bad night. I was flat. I didnt have the best weight cut, and it showed. I had a good first round but then just felt zapped. I felt OK but not my best -- and against someone like Anderson, you have to be your best.Henderson rebounded and won three straight fights, including a highlight-reel knockout of Bisping at UFC 100, and appeared to be closing in on another chance at UFC gold. But the win didnt lead directly to a title shot. Instead, Henderson went on to leave the UFC shortly thereafter and sign with Strikeforce.Its ironic that the win over Bisping led to a title shot more than seven years later. Bisping, 37, has long taken issue with a second punch Henderson landed after the right hand knocked him out, as well as Hendersons approved use of testosterone before the fight. After all, Henderson would have never received this weekends opportunity without that history.I want to beat this guy, Bisping said. Of course, he knocked me out. It was good. But Dan Henderson couldnt beat Anderson Silva. Dan Henderson couldnt win a UFC title. Dan Henderson is famous for one thing -- thats knocking me out at UFC 100. I made your career, Dan. And after UFC 204, that will be eradicated.In a way, fate seems to be back on Hendersons side. Twice he has been a champion of another promotion that was bought and ultimately folded into the UFC. And although he was on the end of terrible luck in 2012, when he had to withdraw from a scheduled title fight against Jon Jones at UFC 151 due to injury, it now seems karma is paying him back with this opportunity.The UFC 204 pay-per-view takes place in the United Kingdom, in a city Bisping refers to as home. Tickets sold out within minutes, according to UFC officials.History has shown that fighters have a hard time retiring off a win, but if Henderson seizes a UFC title on Saturday, its hard to envision a more perfect way to end his career.Im thankful things have worked out the way they did, Henderson said. The UFC bought Strikeforce and me along with it, I guess. That happened twice in my career. Im perfectly happy with where things have turned out. ' ' '